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KMID : 0359719950130020311
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Journal of the Korean Neurological Association
1995 Volume.13 No. 2 p.311 ~ p.318
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Gliomatosis Cerebri: Clinical, Radiological, and Pathological Analysis of Nine Cases
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박경석
전범석/이광우/노재규/이상복/명호진/지제근
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Abstract
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Gliomatosis cerbri is a rare tunror of neuroepithelial origin presenting as deterioration of cognitive function, seizure, and psychomotor retardation.
Since 1988, we have seen nine cases of gliomatosis confirmed by biopsy.
Headache, seizure, visual disturbance, dementia, motor weakness wee the initial predominating clinical features in these cases.
MRI was much better in delineating the extent of tumors by showing ill-defined high signal intensity on T2-weighted images.
Histological examination of brain biopsy disclosed a diffuse proliferation of neoplatic glial cells infiltrating into well-presservedunderlying cytorchitecture.
The diagnosis of glimatosis cerebri was formerly made only at autopsy. However, recent improvements in neuroimaging techniques and biopsy now allow for an temortem diagnosis.
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KEYWORD
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